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Dosing considerations for a theoretical combined protocol No established protocol exists for combining tesamorelin and retatrutide

PLoS One 3 : e2085

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Here we report that these two oncogenic pathways may not act in concert, but act apparently partially antagonistic at least in human GIC models, potentially accounting for disappointing results with inhibition of either pathway in the clinic 29,30,31 , but also providing new concepts on how to modulate these pathways more efficiently to improve the outcome of glioblastoma

We are repeating the same mistake we made then - except now it's higher stakes