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Zeisel SH, Epstein MF, Wurtman RJ

By inhibiting the effects of histamine, antihistamines help reduce discomfort and inflammation caused by APD

Its also involved in nutrient absorption and the synthesis of coenzyme A, which is necessary for the production of ATP

Meraz IM, Majidi M, Meng F, Shao R, Ha MJ, Neri S, et al

In one single-center trial of 72 subjects using a controlled-adverse-environment model, the T4 eye drop did not meet its co-primary endpoints (ocular discomfort and inferior corneal staining) at the primary time point, but it did produce statistically significant improvements on several secondary endpoints, including central and superior corneal staining, with no adverse events reported