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Similarly, when mitochondrial ATP levels go up, ATP inhibits ME2, thereby decreasing pyruvate production (Fig

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For example, a small study with N-acetylcysteine (NAC) infusion reported acute increases in brain GSH concentrations in three healthy older adults (35), while oral doses of NAC have been ineffective (36)

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In this systematic review and meta-analysis, we considered studies eligible for inclusion if: (1) study stylerandomized controlled trials (RCTs)