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S2CID 84080031

Angelica sinensis polysaccharide (ASP) combined with cisplatin increased ferroptosis in cisplatin-resistant ovarian cancer cells through inhibition of GPX4 expression with significant GSH depletion and no obvious toxicity to liver, kidney, and cardiac tissues, ultimately reversed the resistance to cisplatin (Guo et al., 2024)

How cyclosporine A exploits the inflammatory state to penetrate the cell and express its immunomodulatory activity was highlighted by Yi-Hung Lin et al

Apoptosis of uterine leiomyoma cells was also stimulated by the expression of caspase-3, an important mediator for apoptosis, and by caspase-9, an initiator of apoptosis (Malik et al., 2009)

The resulting carcinogenic potency of the dealkylated compound results from the remaining alkyl chain and the number of its remaining atoms