increase glutathione peroxidase system enhancement for cardiac protection: pharmacological options against oxidative stress and ferroptosis Glutathione and the Cofactors

Reed, D

PLoS ONE 10(3):e0120791

When toxins crash the party in your liver, they often create reactive molecules that want to damage your liver cells

Clinical and hematologic features reflect the severity of hemolysis but are not themselves specifically from G6PD deficiency

Glutathiones main roles include: Neutralizing harmful free radicals Acting as a cofactor for several antioxidant enzymes Regenerating vitamins C and E Neutralizing free radicals produced by Phase I liver metabolism of chemical toxins, including formaldehyde, acetaminophen, benzpyrene, and many other compounds Participating in Phase I and Phase II detoxification reactions Adhering to toxins and heavy metals (including mercury) before carrying them out of the body Regulating cellular proliferation and apoptosis Participating in mitochondrial function and the maintenance of mitochondrial DNA Essentially, glutathione is crucial for shielding cells from endogenous and exogenous reactive oxygen and nitrogen species, as well as dealing directly with the causes of oxidative stress such as mercury and pollutants