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Description

Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice

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Vitamin B12 is not produced naturally in the body and must be obtained through diet or injections

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Not a peptide CHEMICAL STRUCTURE Molecular Formula : C 10 H 11 N 2 + Source: PubChem Mechanism of Action 5-Amino-1MQ acts as a highly selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT), blocking the methylation of nicotinamide (a form of vitamin B3) using S-adenosyl methionine (SAM) as a methyl donor

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This provides approximately 4mcg/kg for a 160lb individual, falling within the effective clinical range

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