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A substance or method will be considered for inclusion on the WADA Prohibited List by the WADA List Expert Advisory Group if the substance or method meets two of the following three criteria: It has the potential to enhance or enhances sport performance

PARP1 makes up about 90% of all PARP activity when responding to DNA damage

Normally, glutathione helps neutralize NAPQI, but in an overdose, glutathione stores can become depleted

Caspases: intracellular signaling by proteolysis