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Given the close association between amino acid metabolism and the pathogenesis of perianal fistula, an in-depth investigation into the amino acid metabolic profiles of newly diagnosed and treatment-nave PFCD and CAF patients will not only help to elucidate the pathophysiological nature of these two diseases but may also identify potential diagnostic biomarkers

Of enzymes that converts epoxyeicosatrienoic acids (EETs) to DHETs, the levels of microsomal epoxide hydrolase (EPHX1) positively correlated with fibrosis stage, but not soluble epoxide hydrolase (EPHX2)

Free Radic Biol Med 26(56):538547 Uchida K, Shiraishi M, Naito Y, Torii Y, Nakamura Y, Osawa T (1999) Activation of stress signaling pathways by the end product of lipid peroxidation

I combine cross-cultural, developmental and evolutionary approaches to generate novel perspectives on human social cognition

This group of ion channels play a crucial role in the homeostasis of cations (like sodium, calcium and magnesium) and the regulation of calcium entry into endometrial cells, which is essential for numerous cellular functions such as gene expression, secretory activity and cellular motility