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Despite being primarily insulin-sensitive and being exposed to high concentrations of BG, TGs, FFAs, and insulin, the liver enters a hyper-anabolic state when it continues to generate and store lipids, all of which is improved by APS (Gu et al., 2015

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FIGURE 1 2.4 Physiological parameters Three physiological indicators were used to evaluate the development of the CIA model and the overall efficacy of TGP: body weight, posterior plantar thickness, and AI

Additionally, the antioxidant enzyme activities of GP and superoxide dismutase were reported to be dysregulated in red blood cells and serum of obese individuals compared to controls (27, 28)

10.1016/0092-8674(94)90118-x Cell 91 HumphriesJ