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A clinical research evaluated the biological and clinical impacts of NAC in patients with PD [79], indicating that a combination of intravenous and oral NAC administration in patients with PD increased dopamine transporter binding and improved symptoms

and idiosyncratic DILI, in which the drug causes dose-independent but unpredictable liver damage

Lifestyle modifications, such as reducing caffeine and fat intake, have been suggested to alleviate symptoms, although individual responses can vary significantly

Glutathione is an important nutrient in the body that supports antioxidant defenses, cellular function and the detoxification of liver pathways.

Tal et al., 2008, Tal et al., 2011