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Future clinical trials should consider using updated primary endpoints that do not take years to develop such as such as nerve conduction deficits and a combination of drugs/compounds that are safe for human use combined with proper lifestyle modifications in diet and exercise (132)

Agents such as sorafenib, sulfasalazine, and artesunate have shown efficacy in promoting ferroptotic death in tumor models, particularly in those resistant to apoptosis-based treatments ( Emerging evidence also suggests that ferroptosis is tightly coupled to lipid metabolism, membrane repair systems, and oxidative signaling

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Voloboueva LA, Emery JF, Sun X et al (2013) Inflammatory response of microglial BV-2 cells includes a glycolytic shift and is modulated by mitochondrial glucose-regulated protein 75/mortalin