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8523, revised 1985)

Another nuclear receptor, peroxisome proliferator-activated receptor (PPAR-), modulates gene expression related to inflammation and mediates antimycobacterial responses against M.tb infection by activating the expression of genes associated with autophagy, lysosomal function, and phagosomal maturation through lipid catabolism and upregulation of TFEB transcription[54]

References: AGS (2023): American Geriatrics Society 2023 updated AGS Beers Criteria for potentially inappropriate medication use in older adults

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doi: 10.3389/fphar.2025.1632924 Received 21 May 2025 Accepted 30 June 2025 Published 16 July 2025 Volume 16 - 2025 Edited by Domenico Mattoscio, University of Studies G