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This structural variation confers upon Tocotrienols potent neuroprotective, antioxidant, anti-cancer, and cholesterol-lowering effects, which have been demonstrated in numerous preclinical and clinical studies (Sen et al., 2006, Sen, Khanna, & Roy, 2007, Shrum et al., 2023, Talib et al., 2024)

Inflammatory cytokines and mediators, including TNF-, IL-1, PGE2, IL-6, and VEGF, TGF-1, are among the tumor-associated factors that promote MDSC proliferation, expansion, and differentiation [31]

Under drought conditions, soluble sugars aid in osmotic regulation, reduce water potential, and protect cells from oxidative damage by stabilizing cellular membranes and proteins 1

Small human studies are now starting: one trial in MS is testing oral sodium butyrates effect on MRI and immune markers [263]

Multi-omics approaches provide a more comprehensive understanding of the vaginal microbiome and its interactions with HPV