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PMID: 34303035 Mol Med Rep Exendin4 promotes osteogenic differentiation of adiposederived stem cells and facilitates bone repair

TRIUMPH-4: knee osteoarthritis plus obesity, the trial reported in December 2025

Lactic acid production by tumor cells, as a byproduct of aerobic or anaerobic glycolysis, has also been shown to play a vital role in the M2-like polarization of TAMs, which is mediated by HIF- 1 (294)

Free Radic Biol Med 31:509519 Liu HM, Bian WX, Liu SX, Huang KX (2012) Selenium protects bone marrow stromal cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation by suppressing oxidative stress and ERK signaling pathway