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Experimental investigations indicate that Dihexa interacts with the hepatocyte growth factor (HGF)/c-Met signaling system through modulation of HGF-associated molecular interactions rather than direct activation of the c-Met receptor

P., Stuppner, H

Targets : Uneven skin tone, dull skin, pigmentation, melasma, acne marks, PIH

The following criteria were considered: Full economic evaluations: cost-utility analysis, cost-effectiveness analysis, cost-benefit analysis Economic evaluations reporting incremental cost-effectiveness ratios (i.e., cost per quality-adjusted life year/life years gained or cost per event avoided) Studies in patients with confirmed vitamin B12 deficiency Studies in English Abstracts were reviewed by a single reviewer and, for those studies meeting the eligibility criteria, full-text articles were obtained

& De Meirleir, K