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When GHK complexes with copper, it silences copper's redox activity, preventing the generation of damaging hydroxyl radicals while still allowing copper to be delivered into cells for use as an enzymatic cofactor

While the majority of published data originates from the Sikiric laboratory in Zagreb, independent groups have increasingly contributed to the literature, and the peptide remains a subject of active investigation across multiple areas of preclinical science.

BPC-157, short for Body Protection Compound-157, is a derivative of body protection compound (BPC)

Meanwhile, GHK-CU peptide is of interest for its copper-binding properties, which may participate in metalloproteinase activity regulation and oxidative stress responses through copper-dependent antioxidant enzyme activation