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In contrast, anti-inflammatory signals like IL-4 promote a metabolic state characterized by intact TCA activity and enhanced FAO, which supports tissue repair and resolution of inflammation

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Iron homeostasis, a key determinant of hepatic health, is disrupted in diseases such as hemochromatosis and fibrosis, leading to ferroptosis

PMID: 15 BertagnolioSThwinSSSilvaRNagarajanSJassatWFowlerRet al