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17, 18, 19 In this short video, Dr

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The core mechanisms include: sustained hyperglycemia activating TLR4 on DRG satellite glial cells (SGCs), accompanied by a significant increase in GFAP expression (Liu Y

In the context of CNS oxidative stress, melatonin emerges as a surprisingly prominent player

Our results demonstrated that LPS- exposure induced the inflammatory response, including cytokine expression (IL6, IL-1, TNF) in macrophages, along with Trp-catabolic enzymes IDO1 and associated catabolites Kyn levels in both THP1 and primary KCs