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This is also common in people taking medications like Proton Pump Inhibitors (PPIs) or metformin , which can block the absorption of B12 and other B vitamins

Finally, EBV might occupy a unique and very strategic position in the MS pathophysiological cascade owing to its effects on the immune system, with this virus also implicated in other autoimmune diseases such as rheumatoid arthritis and systemic lupus (James and Robertson, 2012

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evidence for systemic effects via oral route in humans is absent as of this writing