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SKU: 15958189241
Price: 22.52 USD
Availability: InStock
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Neurosci Lett 302:141145 Artuch R, Vilaseca MA, Moreno J, Lambruschini N, Cambra FJ, Campistol J (1999) Decreased serum ubiquinone-10 concentration in phenylketonuria

Fogelman, A

Birth Defects, Decreased IQ, and Neurodevelopmental Disorders Inform pregnant women and women of childbearing potential (including girls beginning the onset of puberty) that use of valproate during pregnancy increases the risk of birth defects, decreased IQ, and neurodevelopmental disorders in children who were exposed in utero [see Warnings and Precautions (5.2, 5.3, 5.4) and Use in Specific Populations (8.1)]

Esta diferencia de concentracin se debe a que en el interior de la mitocondria no se encuentra la enzima catalasa, por lo tanto, GSH es el encargado de inactivar el perxido dehidrgeno generado durante los procesos oxidativos que ocurren en la matriz mitocondrial (7)