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235 The above evidence demonstrates that the MS, SLE, RA, and SS patients have active EBV lytic replication

No large-scale phase 3 trials have been completed

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The consequences of severe hypokalemia can be life-threatening: Cardiac arrhythmias (irregular heartbeats) Muscle weakness and paralysis Respiratory failure (breathing problems) Rhabdomyolysis (breakdown of muscle tissue) Potential cardiac arrest (heart stopping) Patients with poor nutritional status or other metabolic conditions are particularly vulnerable to this complication

95 After 60 days, a significant reduction in pulmonary artery numbers and an increase in the Fulton index and RVSP were noted, indicating RV remodeling and PH