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Conversely, optogenetic activation of DMV-projecting PVN Glu neurons led to significantly increased fecal output and fecal water content, as well as faster motility and small intestinal transit rates in ChR2-expressing mice compared to mCherry-expressing controls (Fig

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preclinical models suggest it fundamentally interacts with the healing cascade itself

2 Gastric Cell Research Laboratory research has examined BPC-157's effects on gastric mucosal cell models, including studies on nitric oxide signaling pathways relevant to gastric cell protection mechanisms in animal models