chac1 glutathione Regulation of ChaC1. Oxidative and ER stress, and viral infection Dysregulated lipids homeostasis disrupts CHAC1-mediated
Dysregulated lipids homeostasis disrupts CHAC1 mediated ferroptosis driving fibroblast growth factor receptor tyrosine kinase inhibitor AZD4547 resistance in gastric cancer ScienceDirect Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease Glutathione (GSH) depletion by ChaC1 results in a more oxidizing Download Scientific Diagram Calcium channel mutants rescue the effect of glutathione depletion. (A) Download Scientific Diagram Mammalian proapoptotic factor ChaC1 and its homologues function as glutamyl cyclotransferases acting specifically on glutathione EMBO Reports Springer Nature Link
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