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While the insights shared in this article are relevant to all altitude dives, its important to note that additional considerations must be considered when diving above 3048m/10,000 ft

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We first examined hydrocortisone PK in patients with adrenal insufficiency and CAH demonstrating that patients have poor disease control on waking with very low cortisol levels and very high ACTH levels which in CAH drives high androgens that cause infertility [10, 11]