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Description

The HO-1/PGC-1 pathway not only protects cells from oxidative stress by strengthening the antioxidant defense system but also provides mitochondrial protection by regulating mitochondrial autophagy and inducing mitochondrial biosynthesis

As these modifications affect both the structure and function of the aging brain, there is the need for developing effective strategies to prevent brain aging [5]

pmid:24717317

Therefore, the investigation of TCM monomers can significantly contribute to understanding the therapeutic mechanisms of both single herbs and herbal formulations in TCM