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The physiological effects of caffeine stem from its action on the central nervous system, where it blocks adenosine receptors, leading to increased neuronal firing and the release of neurotransmitters like dopamine and norepinephrine

78 mTORC1 participates in protein, glucose and lipid metabolism mainly through phosphorylation and activation of p70S6 kinase 1 (S6K1), while mTORC2, an effector of PI3K, contributes to the activation of Akt

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