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The protein level of significantly increased p16 was confirmed in keloid lesions and fibroblasts based on western blot analysis ( p = 0.0007, p = 0.03

Cancer Lett (2000) 151(1):8795.10.1016/S0304-3835(99)00424-3 80 DAutreauxBToledanoMB

doi: 10.1016/S1388-1981(00)00044-5

The acetylation of histones promotes the differentiation of adult hippocampal progenitor cells

30,31 Additionally, reporting MCID thresholds in addition to CFB across measures allows patient-level responses to be considered alongside the average improvement in the study population, which is important given some patients may not respond to treatment