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21 In Gram-negative bacteria, drug entry occurs through porin channels, bilayer diffusion, or passive uptake

Vitamin B12, also known as cobalamin, is a water-soluble vitamin that supports DNA synthesis, red blood cell formation, and neurological function

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Thymoquinone (TQ), a bioactive compound of Nigella sativa seeds, has emerged as a therapeutic candidate for various diseases due to its diverse pharmacological properties (11), including antioxidant, anti-inflammatory, antiviral, anticancer (12, 13), antibacterial (14, 15), immunomodulatory (16), anticoagulant (17), antipsychotic, anxiolytic, antidepressant (18), and anticonvulsant activities (19, 20)