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Similarly, treatment with IL-6 causes changes in the cytoskeleton, leading to increased permeability across cellular barriers through ZO-1 redistribution, actin structure remodeling, and increased actin contractility [83]

The link between caffeine and heart health is not fully understood, but caffeines diuretic effect can lower blood pressure and block a substance that can cause atrial fibrillation, an arrhythmia that can lead to strokes.

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As suggested above, future studies could introduce the counterselection system to yeast strains engineered for GSH overproduction to investigate the potential for further enhancement in those backgrounds