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However, research into ferroptosis mechanisms in CHD remains in its early stages, with significant questions regarding its relationship with other cell death pathways and the clinical efficacy of ferroptosis-targeting interventions requiring further investigation

Increasing evidence shows that ferroptosis can be accompanied by inflammation, and that cells can activate innate immune system factors through ferroptosis stimulation and play a role in regulating inflammation damage, signal transduction, and cell growth 88,89

Comparing the Two: - Efficacy : Both Alpha Arbutin and Hydroquinone are effective skin-lightening agents, but Hydroquinone's potency often leads to quicker results, while Alpha Arbutin takes a more gradual approach

however, the application is limited by indications and usually needs to be combined with lifestyle interventions to reduce the risk of weight rebound

This review delineates the molecular and cellular pathways by which Hg exerts neurotoxic effects, emphasizing its disruption of the glutamateglutamineGABA cycle and the resulting excitotoxic activation of NMDA receptors