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Abadie et al, 2020), segments of 2 cm were obtained from distal intestine and fixed in 4% PBS-paraformaldehyde (ITW Reagents) for histology

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23 Some of the proteins released from mitochondria into the cytoplasm include apoptosis-inducing factor and endonuclease G, both of which have nuclear localization signals and thus translocate to the nucleus, where the endonuclease cleaves DNA, resulting in DNA fragmentation

doi: 10.1038/s41392-023-01367-x 11 RaisRLembergKMTenoraLArwoodMLPalAAltJet al

however, in a previous interim analysis, the authors reported that a protective effect was perceived more clearly in female individuals than in male individuals [107]