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Kat6a +/ mice displayed hyperactivity and learning, memory, and sociability deficits compared with WT mice

103 Insulin resistance, even in the context of normal blood glucose levels, promotes unhealthy lipid metabolism and obesity, activates inflammatory pathways, and reduces NO production, promoting endothelial dysfunction and accelerated atherosclerosis

Polyphenols have been identified as promising candidates due to their broad spectrum of biological properties and low side effects when compared with conventional diabetes medications (Solayman et al., 2016)