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21 The methodical difficulty in this context consists of the large prevalence of disc degeneration in the asymptomatic population

Randolph TL, Amin MB, Ro JY, Ayala AG

The first consists in the study of the expression of single candidate genes already known to be target of redox-regulation, such as cjun43 and NF-B.44 However, since it has been shown that the biological response due to oxidative stress is mediated by the modification of a complex array of genes,45 the study of single candidate genes may not be adequate to solve the complexity of oxidative-stress-based liver pathologies

Compared with the normal control mice, the mRNA and protein expression levels of NF-B p65 in the PBMCs were markedly elevated in the mice with cancer cachexia receiving saline