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Carnosine blocks the AGE formation pathways by binding to these highly active intermediates and neutralizing their reactivity (52)

They also showed that nitration of Tyr residues of TPH has minimal impact on the inhibition of TPH catalytic activity

The monobromobimane adduct was monitored with a scanning fluorescence detector (Waters 2475) with an excitation wavelength of 370 nm and an emission wavelength of 485 nm