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Metabolism of T lymphocytes in health and disease

McKenna RW, Washington LT, Aquino DB, Picker LJ, Kroft SH

If these systems are overwhelmed or unable to limit excessive ROS production, mitochondrial injury, loss of DNA integrity, and shortened lifespan can occur (34, 69, 78, 96, 104, 120, 122, 162, 207, 209, 218, 226229)