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While turmeric is sometimes recommended for kidney health, taking large amounts can damage the kidneys, especially in people with C3G, IC-MPGN, or advanced kidney disease

Peroxisome biogenesis disorders (PBDs) have mainly genetic backgrounds and are caused by incorrect genesis, mainly their assembly, or functional defects of peroxisomes [109]

Impaired oxidative phosphorylation (OXPHOS), elevated reactive oxygen species (ROS) levels, and calcium dysregulation disrupt cellular energetics and extracellular matrix (ECM) homeostasis, contributing to the hallmark features of hEDS

Enzyme assays Anti-cyclooxygenase assay (COX-I/II) A standard previously reported procedure 22 was followed in performing the COX-I/II inhibitory test

Ascorbic acid has direct antioxidant effects, and also it is a substrate for the redox enzyme ascorbate peroxidase, that is particularly important in stress resistance in plants