glutathione peroxidase purpose Reaction mechanism of (GPX) Glutathione Peroxidase from bovine erythrocytes has been used as an oxygen radical scavenger to study its effect on cytotoxicity of 1 The glutathione peroxidase family: Discoveries

The role of microtubules in secretory protein transport

10.1152/ajprenal.00352.2017 26 LeeJ

The discovery of protein aggregates and causative mutations in FUS/TLS 2,3 and TDP-43 (refs 4, 5, 6, 7), two strikingly similar RBPs, as dominant causes of both the fatal adult motor neuron disease amyotrophic lateral sclerosis (ALS) and the second most frequent degenerative cognitive disorder (frontal temporal degeneration (FTD)) has initiated a paradigm shift in research on this pair of diseases, with errors in RNA maturation now a focus as a central component of disease mechanism 1,2,3,4,5,6,7,8

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The role of mtROS in host-pathogen interactions extends to Pseudomonas aeruginosa , where quorum-sensing molecules induce mitochondrial depolarization and oxidative stress, contributing to tissue injury in chronic lung infections ( 3.5 Bacteria-induced mtDNA release and activation of innate immune Mitochondrial damage induced by bacterial effectors often results in mtDNA leakage into the cytosol or extracellular environment