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While lipid droplets have been observed primarily in macrophage models following bacterial infection, the potential of viral infections in cells to elicit a similar response has not been extensively investigated

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A recent Phase III clinical trial focused on gout patients who were intolerant or contraindicated to xanthine oxidase inhibitors (XOIs) revealed that lesinurad monotherapy at a dosage of 400 mg led to a significant incidence of elevated serum creatinine