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doi:10.1016/j.biochi.2016.02.012 [PubMed] [Elsevier] Hanna M, Jaqua E, Nguyen V, Clay J

Vitamin B12 plays a quiet but critical role in how your body produces energy, forms red blood cells, and maintains a functioning nervous system

Gastrointestinal Disturbances Occasional constipation, diarrhea, or dry mouth may occur, especially if the injections contain stimulants or other additives

NNMT inhibition during this peak synthesis window allows more nicotinamide to enter the salvage pathway precisely when the cellular machinery is primed to convert it to NAD+

A major limitation to this study is that the mean dose of IV furosemide prior to hyperdiuresis was 100 mg