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P values were calculated with a twotailed unpaired Student's t test

Skin preparation First, the skin was promptly peeled off the euthanized miniature scent pig

Vitamin B12 sits alongside vitamin D and iron as one of the three deficiencies I check most consistently in Indian women presenting with unexplained fatigue, mood changes, or tingling

The homogenates were then centrifuged at 12,000 rpm for 30 min at 4C

To meet the diagnostic criteria for cEDS, a person must meet: Major criterion 1 AND major criterion 2 OR Major criterion 1 AND three or more minor criteria Major Criteria Skin hyperextensibility and atrophic scarring Generalized joint hypermobility Minor Criteria Easy bruising Soft, doughy skin Skin fragility (or traumatic splitting) Molluscoid pseudotumors Subcutaneous spheroids Hernia (or history thereof) Epicanthal folds Complications of joint hypermobility (e.g., sprains, dislocations/subluxations, pain, flexible flatfoot) Family history of a first-degree relative who meets clinical criteria Hypermobility Spectrum Disorders (HSD) HSD in Adults Adults are diagnosed with HSD if they have symptomatic joint hypermobility that cannot be explained by other conditions