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Some patients experience mild oxidative stress as their bodies shift from higher caloric intake to deficit conditions, theoretically creating a window where cellular antioxidant support might matter

WTSA 2016, 2016

These results demonstrate that deletion of the Igf1 gene in articular cartilage protects against osteoarthritis in mice

Summary diagram (Fig

Finally, biological studies should distinguish redox buffering from redox sensitization using orthogonal redox readouts and appropriate controls (a free phenolic compound, a blank MSN, and a functionalized MSN without the payload)