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For the primary efficacy analysis of actimetry and home diary outcomes, the outcome values were calculated using the measures performed during the planned weeks of assessment (the first and last week of each treatment period) without deviations from the target oral l-dopa dose (that is, a week when the patient did not receive the oral optimized l-dopa dose determined in phase 1 of the DIVE-1 study)

HGF-MET transcripts and proteins were spatially and temporally mapped on rodent brains using various approaches including immunohistochemistry, Western blotting, and in situ hybridization

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doi: 10.1634/theoncologist.2016-0455 89 NorguetEDahanLSeitzJF

Patients with early hereditary optic nerve atrophy, cyanocobalmin hypersensitivity, and those who are pregnant