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Ginkgo biloba further enhanced cognition and mood in patients undergoing ECT and, in rat models of stress-induced depression, mitigated neural damage, restored hippocampal BDNF, and reduced nNOS, highlighting its role as a safe and effective adjunctive therapy for depression and neuroprotection

Furthermore, periodontitis alters the oral microbiota by the creating of an acidic and anaerobic microenvironment while disrupting of host immune tolerance