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FIGURE 8 Influence of H 2 O 2 on the Levels of ROS and Glutathione in the Mutants slr0236 , sll1545 , and slr0236-sll1545 In response to 250 M H 2 O 2 , the mutant sll1545 exhibited a high level of ROS that lasted during 8 h, a time during which we noticed a low and transient decrease of GSH (at 1 h) followed by a strong and temporary increase (at 3 h) of GSSG, followed by a strong and transient increase of GSSG (peak at 8 h)

The combined toxicological effect of this mixturewhich may be additive, synergistic, or antagonisticis almost entirely uncharacterised and represents a more realistic exposure scenario than any single-component study

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites

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