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Importantly, PGC-1 over-expression obviously reduced HFD-induced liver tissue damage, collagen and iron deposition, liver functional impairments, MDA formation and restored liver GSH levels in mice, relative to that in the mice fed with HFD and injected with the control AAV8-NC (Fig

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Discovery of a first-in-class CD38 inhibitor for the treatment of mitochondrial myopathy

13, 74 (2015), Application(s): Assay, Abstract Full Text Coffee and caffeine potentiate the antiamyloidogenic activity of melatonin via inhibition of A oligomerization and modulation of the Tau-mediated pathway in N2a/APP cells: L.F

10.1016/j.molmed.2023.07.002 359 ParkS.-H.LeeJ