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One of the main molecular pathologic mechanisms in this setting is represented by -synuclein aggregation in mitochondria, which leads to the production of reactive oxygen species (ROS) and induces activation of p38 MAPK, a MAP-kinase that triggers the phosphorylation of Drp1 (dynamin-related protein-1), which eventually leads to mitochondrial fission (Martin et al., 2014)

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Oral liposomal glutathione takes 12 hours to reach peak absorption, with symptom improvement (if any) appearing 24 hours after dosing

GSH er den reducerede, stabile form for glutathion