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This is why, for example, alcoholics are more susceptible to acetaminophen toxicity, since alcohol induces the enzyme that is responsible for production of the reactive metabolite from acetaminophen

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They can interact with various immunological receptors, including Dectin-1, complement receptor (CR3), and toll-like receptors (TLR) 2/6

Clearly, larger randomized trials which contain all of the supplements felt to potentially beneficial (the MOXI trial did not include CoQ10) are needed to better elucidate the impact of these therapies on fertility outcomes

However, it is not clear that supplementing dietary antioxidants beyond those typically obtained in a well-balanced diet endows any additional atheroprotective effects