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Waser, Jerome [Angewandte Chemie - International Edition, 2020, vol

Hepatotoxicity with High-Dose Green Tea Extract: Effect of Catechol-O-Methyltransferase and Uridine 5-Diphospho-glucuronosyltransferase 1A4 Genotypes

Other reasons for the failure of translating pre-clinical finding to human disease are the endpoints used in clinical studies for DPN are not sensitive or require greater period for reversal then is allowed for in most studies

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1 Introduction The liver is an important organ involved in the regulation of lipid metabolism, which can convert carbohydrates such as glucose into triglycerides (TGs) and cholesterol, and then secrete it into the blood for peripheral tissue storage and utilization