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OspA 165-175 was mutated to FTLEGALTA to prevent sequence similarities to hLFA L322340 after vaccination (Fig

Although high selectivity of PAG for CSE over CBS has been reported (i.e., an IC 50 of 40 M for the CSE-catalyzed reaction using 1 mM of cysteine as the substrate, with no detectable inhibition of CBS even at 10 mM PAG), it also inhibits several other PLP enzymes, such as aspartate aminotransferase, alanine aminotransferase, and methionine -lyase (Sun et al., 2009)

It can be used as a nanocarrier to facilitate the controlled release of DOX and near-infrared photosensitizer IR780, to achieve the synergistic combined anti-cancer effect of PTT/PDT and chemotherapy

Sikiri P, et al

If you experience persistent fatigue, neurological symptoms, or unexplained anaemia, contact your GP for assessment