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TSRA Wellness Webinar Series

Genome-wide DNA methylation analyses of peripheral blood mononuclear cells (PBMCs) from RA patients show that 10 sites at the DUSP22 promoter region are hypomethylated and associated with erosive RA [113]

Both exercise and dietary interventions have been shown to increase GSH levels, particularly moderate exercise (versus vigorous exercise) and consumption of cruciferous vegetables.Additional therapies include resveratrol, selenium, whey protein, lipoic acid,pycnogenol,spirulina,silymarin,and sulforaphane

Other barrier components include phospholipids within the mucosal surface, epithelial factors including tight junctions, the intestinal immune system including lymphocytes and the gut microbiota [4,68]

One of the challenges is that glutathione production decreases naturally as we age